Dolichyl-diphosphooligosaccharide--protein…

About Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (DAD1) is a protein from Homo sapiens identified by UniProt accession P61803, 113 residues long. MolForge cross-references it against 0 known binders and 89 disease associations.

Target properties

Protein name	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1
UniProt accession	P61803
Gene	DAD1
Organism	Homo sapiens
Length	113 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (89)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.50
COVID-19 · score 0.37
Palmar Fibromatosis · score 0.14
neurofibrillary tangles measurement · score 0.14
narcolepsy-cataplexy syndrome · score 0.12
periodontal measurement · score 0.10
monocyte count · score 0.06
Syndactyly type 2 · score 0.06
syndactyly type 4 · score 0.06
Split hand-split foot malformation · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P61803-F1	alphafold	PREDICTED	95.30	—

Amino-acid sequence (113 residues)

MSASVVSVIS RFLEEYLSST PQRLKLLDAY LLYILLTGAL QFGYCLLVGT FPFNSFLSGF ISCVGSFILA VCLRIQINPQ NKADFQGISP ERAFADFLFA STILHLVVMN FVG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (DAD1)