Large ribosomal subunit protein eL37 (RPL37)

About Large ribosomal subunit protein eL37

Large ribosomal subunit protein eL37 (RPL37) is a protein from Homo sapiens identified by UniProt accession P61927, 97 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.

Target properties

Protein name	Large ribosomal subunit protein eL37
UniProt accession	P61927
Gene	RPL37
Organism	Homo sapiens
Length	97 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (44)

Diseases linked to this target (Open Targets).

Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
influenza · score 0.46
neurodegenerative disease · score 0.36
Becker muscular dystrophy · score 0.29
qualitative or quantitative defects of dystrophin · score 0.26
aniridia · score 0.09
diffuse large B-cell lymphoma · score 0.08
epilepsy · score 0.07
hemophilia A · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P61927-F1	alphafold	PREDICTED	89.47	—

Amino-acid sequence (97 residues)

MTKGTSSFGK RRNKTHTLCR RCGSKAYHLQ KSTCGKCGYP AKRKRKYNWS AKAKRRNTTG TGRMRHLKIV YRRFRHGFRE GTTPKPKRAA VAASSSS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards