Ubiquitin-fold modifier 1 (UFM1)

About Ubiquitin-fold modifier 1

Ubiquitin-fold modifier 1 (UFM1) is a protein from Homo sapiens identified by UniProt accession P61960, 85 residues long. MolForge cross-references it against 0 known binders and 85 disease associations.

Target properties

Protein name	Ubiquitin-fold modifier 1
UniProt accession	P61960
Gene	UFM1
Organism	Homo sapiens
Length	85 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (85)

Diseases linked to this target (Open Targets).

Hypomyelination with atrophy of basal ganglia and cerebellum · score 0.75
neurodegenerative disease · score 0.55
Microcephaly · score 0.37
microcephaly · score 0.37
lysosomal storage disease · score 0.31
schizophrenia · score 0.24
protein measurement · score 0.23
body height · score 0.20
blood protein measurement · score 0.13
oral squamous cell carcinoma · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P61960-F1	alphafold	PREDICTED	91.63	—

Amino-acid sequence (85 residues)

MSKVSFKITL TSDPRLPYKV LSVPESTPFT AVLKFAAEEF KVPAATSAII TNDGIGINPA QTAGNVFLKH GSELRIIPRD RVGSC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards