Nuclear transport factor 2 (NUTF2)

About Nuclear transport factor 2

Nuclear transport factor 2 (NUTF2) is a protein from Homo sapiens identified by UniProt accession P61970, 127 residues long. MolForge cross-references it against 0 known binders and 189 disease associations.

Target properties

Protein name	Nuclear transport factor 2
UniProt accession	P61970
Gene	NUTF2
Organism	Homo sapiens
Length	127 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (189)

Diseases linked to this target (Open Targets).

head and neck squamous cell carcinoma · score 0.09
cancer · score 0.09
high density lipoprotein cholesterol measurement · score 0.08
melanoma · score 0.08
neoplasm · score 0.08
early-onset non-syndromic cataract · score 0.08
cataract 46 juvenile-onset · score 0.07
Total congenital cataract · score 0.06
isolated ectopia lentis · score 0.06
Cataract-microcornea syndrome · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P61970-F1	alphafold	PREDICTED	95.17	—

Amino-acid sequence (127 residues)

MGDKPIWEQI GSSFIQHYYQ LFDNDRTQLG AIYIDASCLT WEGQQFQGKA AIVEKLSSLP FQKIQHSITA QDHQPTPDSC IISMVVGQLK ADEDPIMGFH QMFLLKNIND AWVCTNDMFR LALHNFG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards