About Ras-related protein R-Ras2
Ras-related protein R-Ras2 (RRAS2) is a protein
from Homo sapiens identified by UniProt accession
P62070, 204 residues long.
MolForge cross-references it against 0 known binders and
397 disease associations.
Target properties
| Protein name | Ras-related protein R-Ras2 |
|---|
| UniProt accession | P62070 |
|---|
| Gene | RRAS2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 204 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (397)
Diseases linked to this target (Open Targets).
- Noonan syndrome · score 0.76
- vitamin D measurement · score 0.51
- BMI-adjusted waist-hip ratio · score 0.47
- neurodegenerative disease · score 0.46
- ovarian cancer · score 0.45
- brain measurement · score 0.41
- cortical surface area measurement · score 0.40
- genetic disorder · score 0.40
- body weight · score 0.38
- body height · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P62070-F1 | alphafold | PREDICTED | 86.70 | — |
Amino-acid sequence (204 residues)
MAAAGWRDGS GQEKYRLVVV GGGGVGKSAL TIQFIQSYFV TDYDPTIEDS YTKQCVIDDR AARLDILDTA GQEEFGAMRE QYMRTGEGFL LVFSVTDRGS FEEIYKFQRQ ILRVKDRDEF PMILIGNKAD LDHQRQVTQE EGQQLARQLK VTYMEASAKI RMNVDQAFHE LVRVIRKFQE QECPPSPEPT RKEKDKKGCH CVIF
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