About Tetraspanin-5
Tetraspanin-5 (TSPAN5) is a protein
from Homo sapiens identified by UniProt accession
P62079, 268 residues long.
MolForge cross-references it against 0 known binders and
78 disease associations.
Target properties
| Protein name | Tetraspanin-5 |
|---|
| UniProt accession | P62079 |
|---|
| Gene | TSPAN5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 268 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (78)
Diseases linked to this target (Open Targets).
- alcohol consumption measurement · score 0.41
- adolescent idiopathic scoliosis · score 0.32
- ulcerative colitis · score 0.26
- alcohol use disorder measurement · score 0.26
- alcohol dependence · score 0.25
- prostate cancer · score 0.11
- prostate carcinoma · score 0.11
- Familial prostate cancer · score 0.11
- neoplasm · score 0.10
- hepatocellular carcinoma · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P62079-F1 | alphafold | PREDICTED | 89.22 | — |
Amino-acid sequence (268 residues)
MSGKHYKGPE VSCCIKYFIF GFNVIFWFLG ITFLGIGLWA WNEKGVLSNI SSITDLGGFD PVWLFLVVGG VMFILGFAGC IGALRENTFL LKFFSVFLGI IFFLELTAGV LAFVFKDWIK DQLYFFINNN IRAYRDDIDL QNLIDFTQEY WQCCGAFGAD DWNLNIYFNC TDSNASRERC GVPFSCCTKD PAEDVINTQC GYDARQKPEV DQQIVIYTKG CVPQFEKWLQ DNLTIVAGIF IGIALLQIFG ICLAQNLVSD IEAVRASW
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