About Neuronal calcium sensor 1
Neuronal calcium sensor 1 (NCS1) is a protein
from Homo sapiens identified by UniProt accession
P62166, 190 residues long.
MolForge cross-references it against 0 known binders and
119 disease associations.
Target properties
| Protein name | Neuronal calcium sensor 1 |
|---|
| UniProt accession | P62166 |
|---|
| Gene | NCS1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 190 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (119)
Diseases linked to this target (Open Targets).
- optic cup area measurement · score 0.33
- neurodegenerative disease · score 0.28
- protein measurement · score 0.17
- neoplasm · score 0.08
- cancer · score 0.08
- insulin resistance · score 0.07
- Fuchs endothelial corneal dystrophy · score 0.04
- hemoglobin measurement · score 0.04
- snowflake vitreoretinal degeneration · score 0.04
- Familial ocular anterior segment mesenchymal dysgenesis · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P62166-F1 | alphafold | PREDICTED | 87.80 | — |
Amino-acid sequence (190 residues)
MGKSNSKLKP EVVEELTRKT YFTEKEVQQW YKGFIKDCPS GQLDAAGFQK IYKQFFPFGD PTKFATFVFN VFDENKDGRI EFSEFIQALS VTSRGTLDEK LRWAFKLYDL DNDGYITRNE MLDIVDAIYQ MVGNTVELPE EENTPEKRVD RIFAMMDKNA DGKLTLQEFQ EGSKADPSIV QALSLYDGLV
Explore Neuronal calcium sensor 1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets