Small ribosomal subunit protein uS9 (RPS16)

About Small ribosomal subunit protein uS9

Small ribosomal subunit protein uS9 (RPS16) is a protein from Homo sapiens identified by UniProt accession P62249, 146 residues long. MolForge cross-references it against 0 known binders and 56 disease associations.

Target properties

Protein name	Small ribosomal subunit protein uS9
UniProt accession	P62249
Gene	RPS16
Organism	Homo sapiens
Length	146 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (56)

Diseases linked to this target (Open Targets).

Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
influenza · score 0.46
COVID-19 · score 0.37
severe acute respiratory syndrome · score 0.37
Becker muscular dystrophy · score 0.29
neurodegenerative disease · score 0.26
qualitative or quantitative defects of dystrophin · score 0.26
medulloblastoma · score 0.11
leukocyte count · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P62249-F1	alphafold	PREDICTED	93.90	—

Amino-acid sequence (146 residues)

MPSKGPLQSV QVFGRKKTAT AVAHCKRGNG LIKVNGRPLE MIEPRTLQYK LLEPVLLLGK ERFAGVDIRV RVKGGGHVAQ IYAIRQSISK ALVAYYQKYV DEASKKEIKD ILIQYDRTLL VADPRRCESK KFGGPGARAR YQKSYR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards