About Ubiquitin-conjugating enzyme E2 G1
Ubiquitin-conjugating enzyme E2 G1 (UBE2G1) is a protein
from Homo sapiens identified by UniProt accession
P62253, 170 residues long.
MolForge cross-references it against 0 known binders and
137 disease associations.
Target properties
| Protein name | Ubiquitin-conjugating enzyme E2 G1 |
|---|
| UniProt accession | P62253 |
|---|
| Gene | UBE2G1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 170 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (137)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- waist-hip ratio · score 0.28
- BMI-adjusted waist-hip ratio · score 0.27
- type 1 diabetes mellitus · score 0.22
- monocyte percentage of leukocytes · score 0.17
- lymphocyte count · score 0.07
- hemoglobin measurement · score 0.06
- multiple epiphyseal dysplasia type 5 · score 0.06
- refractive error · score 0.05
- hip dysplasia, Beukes type · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P62253-F1 | alphafold | PREDICTED | 94.12 | — |
Amino-acid sequence (170 residues)
MTELQSALLL RRQLAELNKN PVEGFSAGLI DDNDLYRWEV LIIGPPDTLY EGGVFKAHLT FPKDYPLRPP KMKFITEIWH PNVDKNGDVC ISILHEPGED KYGYEKPEER WLPIHTVETI MISVISMLAD PNGDSPANVD AAKEWREDRN GEFKRKVARC VRKSQETAFE
Explore Ubiquitin-conjugating enzyme E2 G1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets