About Ubiquitin-conjugating enzyme E2 H
Ubiquitin-conjugating enzyme E2 H (UBE2H) is a protein
from Homo sapiens identified by UniProt accession
P62256, 183 residues long.
MolForge cross-references it against 0 known binders and
54 disease associations.
Target properties
| Protein name | Ubiquitin-conjugating enzyme E2 H |
|---|
| UniProt accession | P62256 |
|---|
| Gene | UBE2H |
|---|
| Organism | Homo sapiens |
|---|
| Length | 183 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (54)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- mean corpuscular volume · score 0.45
- lymphocyte count · score 0.42
- mean corpuscular hemoglobin concentration · score 0.42
- erythrocyte count · score 0.41
- mean corpuscular hemoglobin · score 0.40
- glomerular filtration rate · score 0.37
- red blood cell density measurement · score 0.37
- monocyte count · score 0.36
- mean reticulocyte volume · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P62256-F1 | alphafold | PREDICTED | 89.31 | — |
Amino-acid sequence (183 residues)
MSSPSPGKRR MDTDVVKLIE SKHEVTILGG LNEFVVKFYG PQGTPYEGGV WKVRVDLPDK YPFKSPSIGF MNKIFHPNID EASGTVCLDV INQTWTALYD LTNIFESFLP QLLAYPNPID PLNGDAAAMY LHRPEEYKQK IKEYIQKYAT EEALKEQEEG TGDSSSESSM SDFSEDEAQD MEL
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