Small ribosomal subunit protein uS11 (RPS14)

About Small ribosomal subunit protein uS11

Small ribosomal subunit protein uS11 (RPS14) is a protein from Homo sapiens identified by UniProt accession P62263, 151 residues long. MolForge cross-references it against 0 known binders and 79 disease associations.

Target properties

Protein name	Small ribosomal subunit protein uS11
UniProt accession	P62263
Gene	RPS14
Organism	Homo sapiens
Length	151 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (79)

Diseases linked to this target (Open Targets).

Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
influenza · score 0.46
COVID-19 · score 0.37
severe acute respiratory syndrome · score 0.37
Becker muscular dystrophy · score 0.29
qualitative or quantitative defects of dystrophin · score 0.26
aniridia · score 0.09
diffuse large B-cell lymphoma · score 0.08
non-Hodgkins lymphoma · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P62263-F1	alphafold	PREDICTED	90.12	—

Amino-acid sequence (151 residues)

MAPRKGKEKK EEQVISLGPQ VAEGENVFGV CHIFASFNDT FVHVTDLSGK ETICRVTGGM KVKADRDESS PYAAMLAAQD VAQRCKELGI TALHIKLRAT GGNRTKTPGP GAQSALRALA RSGMKIGRIE DVTPIPSDST RRKGGRRGRR L

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards