About Small ribosomal subunit protein uS12
Small ribosomal subunit protein uS12 (RPS23) is a protein
from Homo sapiens identified by UniProt accession
P62266, 143 residues long.
MolForge cross-references it against 0 known binders and
78 disease associations.
Target properties
| Protein name | Small ribosomal subunit protein uS12 |
|---|
| UniProt accession | P62266 |
|---|
| Gene | RPS23 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 143 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (78)
Diseases linked to this target (Open Targets).
- brachycephaly, trichomegaly, and developmental delay · score 0.59
- Duchenne muscular dystrophy · score 0.50
- cystic fibrosis · score 0.50
- influenza · score 0.46
- severe acute respiratory syndrome · score 0.37
- COVID-19 · score 0.37
- Becker muscular dystrophy · score 0.29
- qualitative or quantitative defects of dystrophin · score 0.26
- mathematical ability · score 0.24
- cognitive function measurement · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P62266-F1 | alphafold | PREDICTED | 94.90 | — |
Amino-acid sequence (143 residues)
MGKCRGLRTA RKLRSHRRDQ KWHDKQYKKA HLGTALKANP FGGASHAKGI VLEKVGVEAK QPNSAIRKCV RVQLIKNGKK ITAFVPNDGC LNFIEENDEV LVAGFGRKGH AVGDIPGVRF KVVKVANVSL LALYKGKKER PRS
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