About Small ribosomal subunit protein uS13
Small ribosomal subunit protein uS13 (RPS18) is a protein
from Homo sapiens identified by UniProt accession
P62269, 152 residues long.
MolForge cross-references it against 0 known binders and
42 disease associations.
Target properties
| Protein name | Small ribosomal subunit protein uS13 |
|---|
| UniProt accession | P62269 |
|---|
| Gene | RPS18 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 152 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (42)
Diseases linked to this target (Open Targets).
- Duchenne muscular dystrophy · score 0.50
- cystic fibrosis · score 0.50
- influenza · score 0.46
- severe acute respiratory syndrome · score 0.37
- COVID-19 · score 0.37
- Becker muscular dystrophy · score 0.29
- qualitative or quantitative defects of dystrophin · score 0.26
- neurodegenerative disease · score 0.16
- late-onset Alzheimers disease · score 0.14
- triple-negative breast cancer · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P62269-F1 | alphafold | PREDICTED | 88.67 | — |
Amino-acid sequence (152 residues)
MSLVIPEKFQ HILRVLNTNI DGRRKIAFAI TAIKGVGRRY AHVVLRKADI DLTKRAGELT EDEVERVITI MQNPRQYKIP DWFLNRQKDV KDGKYSQVLA NGLDNKLRED LERLKKIRAH RGLRHFWGLR VRGQHTKTTG RRGRTVGVSK KK
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