Small ribosomal subunit protein uS14 (RPS29)

About Small ribosomal subunit protein uS14

Small ribosomal subunit protein uS14 (RPS29) is a protein from Homo sapiens identified by UniProt accession P62273, 56 residues long. MolForge cross-references it against 0 known binders and 70 disease associations.

Target properties

Protein name	Small ribosomal subunit protein uS14
UniProt accession	P62273
Gene	RPS29
Organism	Homo sapiens
Length	56 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (70)

Diseases linked to this target (Open Targets).

Blackfan-Diamond anemia · score 0.64
Diamond-Blackfan anemia · score 0.56
Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
influenza · score 0.46
COVID-19 · score 0.37
severe acute respiratory syndrome · score 0.37
Becker muscular dystrophy · score 0.29
clear cell renal carcinoma · score 0.27
endometrial cancer · score 0.27

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P62273-F1	alphafold	PREDICTED	93.70	—

Amino-acid sequence (56 residues)

MGHQQLYWSH PRKFGQGSRS CRVCSNRHGL IRKYGLNMCR QCFRQYAKDI GFIKLD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards