Small ribosomal subunit protein uS15 (RPS13)

About Small ribosomal subunit protein uS15

Small ribosomal subunit protein uS15 (RPS13) is a protein from Homo sapiens identified by UniProt accession P62277, 151 residues long. MolForge cross-references it against 0 known binders and 72 disease associations.

Target properties

Protein name	Small ribosomal subunit protein uS15
UniProt accession	P62277
Gene	RPS13
Organism	Homo sapiens
Length	151 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (72)

Diseases linked to this target (Open Targets).

Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
influenza · score 0.46
severe acute respiratory syndrome · score 0.37
COVID-19 · score 0.37
Becker muscular dystrophy · score 0.29
clear cell renal carcinoma · score 0.27
qualitative or quantitative defects of dystrophin · score 0.26
pancreatic adenocarcinoma · score 0.22
smoking behavior · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P62277-F1	alphafold	PREDICTED	94.03	—

Amino-acid sequence (151 residues)

MGRMHAPGKG LSQSALPYRR SVPTWLKLTS DDVKEQIYKL AKKGLTPSQI GVILRDSHGV AQVRFVTGNK ILRILKSKGL APDLPEDLYH LIKKAVAVRK HLERNRKDKD AKFRLILIES RIHRLARYYK TKRVLPPNWK YESSTASALV A

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards