About Protein BTG1
Protein BTG1 (BTG1) is a protein
from Homo sapiens identified by UniProt accession
P62324, 171 residues long.
MolForge cross-references it against 0 known binders and
132 disease associations.
Target properties
| Protein name | Protein BTG1 |
| UniProt accession | P62324 |
| Gene | BTG1 |
| Organism | Homo sapiens |
| Length | 171 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (132)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.45
- diffuse large B-cell lymphoma · score 0.44
- eosinophil percentage of leukocytes · score 0.42
- lymphoid neoplasm · score 0.42
- heel bone mineral density · score 0.37
- Small Intestinal Diffuse Large B-Cell Lymphoma · score 0.37
- Central Nervous System Lymphoma · score 0.37
- diffuse large B-cell lymphoma of the central nervous system · score 0.37
- body height · score 0.35
- multiple myeloma · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-P62324-F1 | alphafold | PREDICTED | 81.38 | — |
Amino-acid sequence (171 residues)
MHPFYTRAAT MIGEIAAAVS FISKFLRTKG LTSERQLQTF SQSLQELLAE HYKHHWFPEK PCKGSGYRCI RINHKMDPLI GQAAQRIGLS SQELFRLLPS ELTLWVDPYE VSYRIGEDGS ICVLYEASPA GGSTQNSTNV QMVDSRISCK EELLLGRTSP SKNYNMMTVS G
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