Protein BTG1 (BTG1)

Homo sapiens — UniProt P62324

Gene: BTG1Homo sapiensSwissProt reviewed

About Protein BTG1

Protein BTG1 (BTG1) is a protein from Homo sapiens identified by UniProt accession P62324, 171 residues long. MolForge cross-references it against 0 known binders and 132 disease associations.

Target properties

Protein nameProtein BTG1
UniProt accessionP62324
GeneBTG1
OrganismHomo sapiens
Length171 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (132)

Diseases linked to this target (Open Targets).

  • eosinophil count · score 0.45
  • diffuse large B-cell lymphoma · score 0.44
  • eosinophil percentage of leukocytes · score 0.42
  • lymphoid neoplasm · score 0.42
  • heel bone mineral density · score 0.37
  • Small Intestinal Diffuse Large B-Cell Lymphoma · score 0.37
  • Central Nervous System Lymphoma · score 0.37
  • diffuse large B-cell lymphoma of the central nervous system · score 0.37
  • body height · score 0.35
  • multiple myeloma · score 0.31

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P62324-F1alphafoldPREDICTED81.38—

Amino-acid sequence (171 residues)

MHPFYTRAAT MIGEIAAAVS FISKFLRTKG LTSERQLQTF SQSLQELLAE HYKHHWFPEK PCKGSGYRCI RINHKMDPLI GQAAQRIGLS SQELFRLLPS ELTLWVDPYE VSYRIGEDGS ICVLYEASPA GGSTQNSTNV QMVDSRISCK EELLLGRTSP SKNYNMMTVS G

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Quick facts

UniProtP62324
GeneBTG1
OrganismHomo sapiens
Length171
Binders0
Diseases132
View on UniProt