About Thioredoxin reductase-like selenoprotein T
Thioredoxin reductase-like selenoprotein T (SELENOT) is a protein
from Homo sapiens identified by UniProt accession
P62341, 195 residues long.
MolForge cross-references it against 0 known binders and
42 disease associations.
Target properties
| Protein name | Thioredoxin reductase-like selenoprotein T |
|---|
| UniProt accession | P62341 |
|---|
| Gene | SELENOT |
|---|
| Organism | Homo sapiens |
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| Length | 195 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (42)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.13
- response to vaccine · score 0.13
- congenital hypothyroidism · score 0.04
- Brugada syndrome · score 0.03
- hypertrophic cardiomyopathy 6 · score 0.03
- hypertrophic cardiomyopathy · score 0.03
- atrial conduction disease · score 0.03
- dilated cardiomyopathy 1E · score 0.03
- glioblastoma · score 0.01
- acute myocardial infarction · score 0.01
Amino-acid sequence (195 residues)
MRLLLLLLVA ASAMVRSEAS ANLGGVPSKR LKMQYATGPL LKFQICVSUG YRRVFEEYMR VISQRYPDIR IEGENYLPQP IYRHIASFLS VFKLVLIGLI IVGKDPFAFF GMQAPSIWQW GQENKVYACM MVFFLSNMIE NQCMSTGAFE ITLNDVPVWS KLESGHLPSM QQLVQILDNE MKLNVHMDSI PHHRS
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