About Large ribosomal subunit protein eL8
Large ribosomal subunit protein eL8 (RPL7A) is a protein
from Homo sapiens identified by UniProt accession
P62424, 266 residues long.
MolForge cross-references it against 0 known binders and
40 disease associations.
Target properties
| Protein name | Large ribosomal subunit protein eL8 |
|---|
| UniProt accession | P62424 |
|---|
| Gene | RPL7A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 266 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (40)
Diseases linked to this target (Open Targets).
- Duchenne muscular dystrophy · score 0.50
- cystic fibrosis · score 0.50
- influenza · score 0.46
- Becker muscular dystrophy · score 0.29
- endometrial cancer · score 0.27
- qualitative or quantitative defects of dystrophin · score 0.26
- aniridia · score 0.09
- diffuse large B-cell lymphoma · score 0.08
- hemophilia A · score 0.07
- non-Hodgkins lymphoma · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P62424-F1 | alphafold | PREDICTED | 90.64 | — |
Amino-acid sequence (266 residues)
MPKGKKAKGK KVAPAPAVVK KQEAKKVVNP LFEKRPKNFG IGQDIQPKRD LTRFVKWPRY IRLQRQRAIL YKRLKVPPAI NQFTQALDRQ TATQLLKLAH KYRPETKQEK KQRLLARAEK KAAGKGDVPT KRPPVLRAGV NTVTTLVENK KAQLVVIAHD VDPIELVVFL PALCRKMGVP YCIIKGKARL GRLVHRKTCT TVAFTQVNSE DKGALAKLVE AIRTNYNDRY DEIRRHWGGN VLGPKSVARI AKLEKAKAKE LATKLG
Explore Large ribosomal subunit protein eL8 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets