About CCHC-type zinc finger nucleic acid binding protein
CCHC-type zinc finger nucleic acid binding protein (CNBP) is a protein
from Homo sapiens identified by UniProt accession
P62633, 177 residues long.
MolForge cross-references it against 0 known binders and
197 disease associations.
Target properties
| Protein name | CCHC-type zinc finger nucleic acid binding protein |
|---|
| UniProt accession | P62633 |
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| Gene | CNBP |
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| Organism | Homo sapiens |
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| Length | 177 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (197)
Diseases linked to this target (Open Targets).
- myotonic dystrophy type 2 · score 0.51
- Proximal myotonic myopathy · score 0.50
- breast ductal adenocarcinoma · score 0.37
- carcinoma of liver and intrahepatic biliary tract · score 0.37
- hepatocellular carcinoma · score 0.28
- lung adenocarcinoma · score 0.28
- esophageal adenocarcinoma · score 0.28
- gastric carcinoma · score 0.28
- acute myeloid leukemia · score 0.28
- cutaneous melanoma · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P62633-F1 | alphafold | PREDICTED | 70.95 | — |
Amino-acid sequence (177 residues)
MSSNECFKCG RSGHWARECP TGGGRGRGMR SRGRGGFTSD RGFQFVSSSL PDICYRCGES GHLAKDCDLQ EDACYNCGRG GHIAKDCKEP KREREQCCYN CGKPGHLARD CDHADEQKCY SCGEFGHIQK DCTKVKCYRC GETGHVAINC SKTSEVNCYR CGESGHLARE CTIEATA
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