Protein yippee-like 5 (YPEL5)

Homo sapiens — UniProt P62699

Gene: YPEL5Homo sapiensSwissProt reviewed

About Protein yippee-like 5

Protein yippee-like 5 (YPEL5) is a protein from Homo sapiens identified by UniProt accession P62699, 121 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.

Target properties

Protein nameProtein yippee-like 5
UniProt accessionP62699
GeneYPEL5
OrganismHomo sapiens
Length121 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (32)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.52
  • sleep duration · score 0.19
  • triglyceride measurement · score 0.19
  • eosinophil count · score 0.07
  • rheumatoid arthritis · score 0.06
  • nonpapillary renal cell carcinoma · score 0.04
  • lymphocyte count · score 0.03
  • total blood protein measurement · score 0.03
  • eosinophil percentage of leukocytes · score 0.03
  • celiac disease · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P62699-F1alphafoldPREDICTED93.06—

Amino-acid sequence (121 residues)

MGRIFLDHIG GTRLFSCANC DTILTNRSEL ISTRFTGATG RAFLFNKVVN LQYSEVQDRV MLTGRHMVRD VSCKNCNSKL GWIYEFATED SQRYKEGRVI LERALVRESE GFEEHVPSDN S

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Quick facts

UniProtP62699
GeneYPEL5
OrganismHomo sapiens
Length121
Binders0
Diseases32
View on UniProt