Small ribosomal subunit protein eS4, X isoform (RPS4X)

About Small ribosomal subunit protein eS4, X isoform

Small ribosomal subunit protein eS4, X isoform (RPS4X) is a protein from Homo sapiens identified by UniProt accession P62701, 263 residues long. MolForge cross-references it against 0 known binders and 81 disease associations.

Target properties

Protein name	Small ribosomal subunit protein eS4, X isoform
UniProt accession	P62701
Gene	RPS4X
Organism	Homo sapiens
Length	263 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (81)

Diseases linked to this target (Open Targets).

Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
influenza · score 0.46
neurodegenerative disease · score 0.46
COVID-19 · score 0.37
severe acute respiratory syndrome · score 0.37
Becker muscular dystrophy · score 0.29
qualitative or quantitative defects of dystrophin · score 0.26
glioblastoma multiforme · score 0.15
aniridia · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P62701-F1	alphafold	PREDICTED	95.57	—

Amino-acid sequence (263 residues)

MARGPKKHLK RVAAPKHWML DKLTGVFAPR PSTGPHKLRE CLPLIIFLRN RLKYALTGDE VKKICMQRFI KIDGKVRTDI TYPAGFMDVI SIDKTGENFR LIYDTKGRFA VHRITPEEAK YKLCKVRKIF VGTKGIPHLV THDARTIRYP DPLIKVNDTI QIDLETGKIT DFIKFDTGNL CMVTGGANLG RIGVITNRER HPGSFDVVHV KDANGNSFAT RLSNIFVIGK GNKPWISLPR GKGIRLTIAE ERDKRLAAKQ SSG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards