Rho-related GTP-binding protein RhoB (RHOB)

About Rho-related GTP-binding protein RhoB

Rho-related GTP-binding protein RhoB (RHOB) is a protein from Homo sapiens identified by UniProt accession P62745, 196 residues long. MolForge cross-references it against 0 known binders and 202 disease associations.

Target properties

Protein name	Rho-related GTP-binding protein RhoB
UniProt accession	P62745
Gene	RHOB
Organism	Homo sapiens
Length	196 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P62745-F1	alphafold	PREDICTED	92.23	—

Amino-acid sequence (196 residues)

MAAIRKKLVV VGDGACGKTC LLIVFSKDEF PEVYVPTVFE NYVADIEVDG KQVELALWDT AGQEDYDRLR PLSYPDTDVI LMCFSVDSPD SLENIPEKWV PEVKHFCPNV PIILVANKKD LRSDEHVRTE LARMKQEPVR TDDGRAMAVR IQAYDYLECS AKTKEGVREV FETATRAALQ KRYGSQNGCI NCCKVL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards