Large ribosomal subunit protein uL23 (RPL23A)

About Large ribosomal subunit protein uL23

Large ribosomal subunit protein uL23 (RPL23A) is a protein from Homo sapiens identified by UniProt accession P62750, 156 residues long. MolForge cross-references it against 0 known binders and 59 disease associations.

Target properties

Protein name	Large ribosomal subunit protein uL23
UniProt accession	P62750
Gene	RPL23A
Organism	Homo sapiens
Length	156 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (59)

Diseases linked to this target (Open Targets).

Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
influenza · score 0.46
Becker muscular dystrophy · score 0.29
endometrial cancer · score 0.27
qualitative or quantitative defects of dystrophin · score 0.26
aniridia · score 0.09
diffuse large B-cell lymphoma · score 0.08
epilepsy · score 0.07
hemophilia A · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P62750-F1	alphafold	PREDICTED	89.30	—

Amino-acid sequence (156 residues)

MAPKAKKEAP APPKAEAKAK ALKAKKAVLK GVHSHKKKKI RTSPTFRRPK TLRLRRQPKY PRKSAPRRNK LDHYAIIKFP LTTESAMKKI EDNNTLVFIV DVKANKHQIK QAVKKLYDID VAKVNTLIRP DGEKKAYVRL APDYDALDVA NKIGII

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards