About Small ribosomal subunit protein eS6
Small ribosomal subunit protein eS6 (RPS6) is a protein
from Homo sapiens identified by UniProt accession
P62753, 249 residues long.
MolForge cross-references it against 0 known binders and
299 disease associations.
Target properties
| Protein name | Small ribosomal subunit protein eS6 |
|---|
| UniProt accession | P62753 |
|---|
| Gene | RPS6 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 249 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (299)
Diseases linked to this target (Open Targets).
- Duchenne muscular dystrophy · score 0.51
- cystic fibrosis · score 0.50
- influenza · score 0.46
- cancer · score 0.39
- COVID-19 · score 0.37
- severe acute respiratory syndrome · score 0.37
- Becker muscular dystrophy · score 0.29
- Red cell distribution width · score 0.28
- breast adenocarcinoma · score 0.28
- endometrial cancer · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P62753-F1 | alphafold | PREDICTED | 94.19 | — |
Amino-acid sequence (249 residues)
MKLNISFPAT GCQKLIEVDD ERKLRTFYEK RMATEVAADA LGEEWKGYVV RISGGNDKQG FPMKQGVLTH GRVRLLLSKG HSCYRPRRTG ERKRKSVRGC IVDANLSVLN LVIVKKGEKD IPGLTDTTVP RRLGPKRASR IRKLFNLSKE DDVRQYVVRK PLNKEGKKPR TKAPKIQRLV TPRVLQHKRR RIALKKQRTK KNKEEAAEYA KLLAKRMKEA KEKRQEQIAK RRRLSSLRAS TSKSESSQK
Explore Small ribosomal subunit protein eS6 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets