Histone H2B type 1-C/E/F/G/I (H2BC4)

About Histone H2B type 1-C/E/F/G/I

Histone H2B type 1-C/E/F/G/I (H2BC4) is a protein from Homo sapiens identified by UniProt accession P62807, 126 residues long. MolForge cross-references it against 0 known binders and 182 disease associations.

Target properties

Protein name	Histone H2B type 1-C/E/F/G/I
UniProt accession	P62807
Gene	H2BC4
Organism	Homo sapiens
Length	126 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (182)

Diseases linked to this target (Open Targets).

infectious disease · score 0.50
viral disease · score 0.50
mean corpuscular hemoglobin · score 0.43
breast carcinoma · score 0.39
cancer · score 0.37
melanoma · score 0.37
hemoglobin measurement · score 0.33
mean corpuscular hemoglobin concentration · score 0.30
Red cell distribution width · score 0.29
iron metabolism disease · score 0.29

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P62807-F1	alphafold	PREDICTED	88.13	—

Amino-acid sequence (126 residues)

MPEPAKSAPA PKKGSKKAVT KAQKKDGKKR KRSRKESYSV YVYKVLKQVH PDTGISSKAM GIMNSFVNDI FERIAGEASR LAHYNKRSTI TSREIQTAVR LLLPGELAKH AVSEGTKAVT KYTSSK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards