GTP-binding nuclear protein Ran (RAN)

About GTP-binding nuclear protein Ran

GTP-binding nuclear protein Ran (RAN) is a protein from Homo sapiens identified by UniProt accession P62826, 216 residues long. MolForge cross-references it against 0 known binders and 207 disease associations.

Target properties

Protein name	GTP-binding nuclear protein Ran
UniProt accession	P62826
Gene	RAN
Organism	Homo sapiens
Length	216 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (1)

DrugCentral-linked approved drugs that act on this protein.

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P62826-F1	alphafold	PREDICTED	88.62	—

Amino-acid sequence (216 residues)

MAAQGEPQVQ FKLVLVGDGG TGKTTFVKRH LTGEFEKKYV ATLGVEVHPL VFHTNRGPIK FNVWDTAGQE KFGGLRDGYY IQAQCAIIMF DVTSRVTYKN VPNWHRDLVR VCENIPIVLC GNKVDIKDRK VKAKSIVFHR KKNLQYYDIS AKSNYNFEKP FLWLARKLIG DPNLEFVAMP ALAPPEVVMD PALAAQYEHD LEVAQTTALP DEDDDL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards