About Large ribosomal subunit protein uL14
Large ribosomal subunit protein uL14 (RPL23) is a protein
from Homo sapiens identified by UniProt accession
P62829, 140 residues long.
MolForge cross-references it against 0 known binders and
43 disease associations.
Target properties
| Protein name | Large ribosomal subunit protein uL14 |
|---|
| UniProt accession | P62829 |
|---|
| Gene | RPL23 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 140 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (43)
Diseases linked to this target (Open Targets).
- Duchenne muscular dystrophy · score 0.50
- cystic fibrosis · score 0.50
- Diamond-Blackfan anemia · score 0.46
- influenza · score 0.46
- Becker muscular dystrophy · score 0.29
- qualitative or quantitative defects of dystrophin · score 0.26
- appendicular lean mass · score 0.22
- serum gamma-glutamyl transferase measurement · score 0.10
- diffuse large B-cell lymphoma · score 0.09
- aniridia · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P62829-F1 | alphafold | PREDICTED | 92.61 | — |
Amino-acid sequence (140 residues)
MSKRGRGGSS GAKFRISLGL PVGAVINCAD NTGAKNLYII SVKGIKGRLN RLPAAGVGDM VMATVKKGKP ELRKKVHPAV VIRQRKSYRR KDGVFLYFED NAGVIVNNKG EMKGSAITGP VAKECADLWP RIASNAGSIA
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