Ubiquitin-conjugating enzyme E2 D2 (UBE2D2)

About Ubiquitin-conjugating enzyme E2 D2

Ubiquitin-conjugating enzyme E2 D2 (UBE2D2) is a protein from Homo sapiens identified by UniProt accession P62837, 147 residues long. MolForge cross-references it against 0 known binders and 56 disease associations.

Target properties

Protein name	Ubiquitin-conjugating enzyme E2 D2
UniProt accession	P62837
Gene	UBE2D2
Organism	Homo sapiens
Length	147 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (56)

Diseases linked to this target (Open Targets).

body height · score 0.26
breast adenocarcinoma · score 0.25
sitting height measurement · score 0.21
ovarian carcinoma · score 0.17
cystatin C measurement · score 0.15
drug use measurement · score 0.15
breast cancer · score 0.08
non-small cell lung carcinoma · score 0.07
platelet count · score 0.06
precocious puberty, central, 2 · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P62837-F1	alphafold	PREDICTED	96.47	—

Amino-acid sequence (147 residues)

MALKRIHKEL NDLARDPPAQ CSAGPVGDDM FHWQATIMGP NDSPYQGGVF FLTIHFPTDY PFKPPKVAFT TRIYHPNINS NGSICLDILR SQWSPALTIS KVLLSICSLL CDPNPDDPLV PEIARIYKTD REKYNRIARE WTQKYAM

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards