Small ribosomal subunit protein eS26 (RPS26)

About Small ribosomal subunit protein eS26

Small ribosomal subunit protein eS26 (RPS26) is a protein from Homo sapiens identified by UniProt accession P62854, 115 residues long. MolForge cross-references it against 0 known binders and 145 disease associations.

Target properties

Protein name	Small ribosomal subunit protein eS26
UniProt accession	P62854
Gene	RPS26
Organism	Homo sapiens
Length	115 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (145)

Diseases linked to this target (Open Targets).

Blackfan-Diamond anemia · score 0.79
Diamond-Blackfan anemia · score 0.74
Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
influenza · score 0.46
Cleft palate · score 0.39
severe acute respiratory syndrome · score 0.37
COVID-19 · score 0.37
cleft palate · score 0.37
Abnormal radial ray morphology · score 0.37

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P62854-F1	alphafold	PREDICTED	85.82	—

Amino-acid sequence (115 residues)

MTKKRRNNGR AKKGRGHVQP IRCTNCARCV PKDKAIKKFV IRNIVEAAAV RDISEASVFD AYVLPKLYVK LHYCVSCAIH SKVVRNRSRE ARKDRTPPPR FRPAGAAPRP PPKPM

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards