Small ribosomal subunit protein eS28 (RPS28)

About Small ribosomal subunit protein eS28

Small ribosomal subunit protein eS28 (RPS28) is a protein from Homo sapiens identified by UniProt accession P62857, 69 residues long. MolForge cross-references it against 0 known binders and 57 disease associations.

Target properties

Protein name	Small ribosomal subunit protein eS28
UniProt accession	P62857
Gene	RPS28
Organism	Homo sapiens
Length	69 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (57)

Diseases linked to this target (Open Targets).

Diamond-Blackfan anemia · score 0.55
Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
Blackfan-Diamond anemia · score 0.49
influenza · score 0.46
COVID-19 · score 0.37
severe acute respiratory syndrome · score 0.37
Becker muscular dystrophy · score 0.29
endometrial cancer · score 0.27
qualitative or quantitative defects of dystrophin · score 0.26

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P62857-F1	alphafold	PREDICTED	91.02	—

Amino-acid sequence (69 residues)

MDTSRVQPIK LARVTKVLGR TGSQGQCTQV RVEFMDDTSR SIIRNVKGPV REGDVLTLLE SEREARRLR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards