Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein (FAU)

Homo sapiens — UniProt P62861

Gene: FAUHomo sapiensSwissProt reviewed

About Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein

Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein (FAU) is a protein from Homo sapiens identified by UniProt accession P62861, 133 residues long. MolForge cross-references it against 0 known binders and 57 disease associations.

Target properties

Protein nameUbiquitin-like FUBI-ribosomal protein eS30 fusion protein
UniProt accessionP62861
GeneFAU
OrganismHomo sapiens
Length133 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (57)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.52
  • Duchenne muscular dystrophy · score 0.50
  • cystic fibrosis · score 0.50
  • influenza · score 0.46
  • severe acute respiratory syndrome · score 0.37
  • COVID-19 · score 0.37
  • Becker muscular dystrophy · score 0.29
  • clear cell renal carcinoma · score 0.27
  • qualitative or quantitative defects of dystrophin · score 0.26
  • glioblastoma multiforme · score 0.15

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P62861-F1alphafoldPREDICTED91.00—

Amino-acid sequence (133 residues)

MQLFVRAQEL HTFEVTGQET VAQIKAHVAS LEGIAPEDQV VLLAGAPLED EATLGQCGVE ALTTLEVAGR MLGGKVHGSL ARAGKVRGQT PKVAKQEKKK KKTGRAKRRM QYNRRFVNVV PTFGKKKGPN ANS

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Quick facts

UniProtP62861
GeneFAU
OrganismHomo sapiens
Length133
Binders0
Diseases57
View on UniProt