E3 ubiquitin-protein ligase RBX1 (RBX1)

About E3 ubiquitin-protein ligase RBX1

E3 ubiquitin-protein ligase RBX1 (RBX1) is a protein from Homo sapiens identified by UniProt accession P62877, 108 residues long. MolForge cross-references it against 0 known binders and 265 disease associations.

Target properties

Protein name	E3 ubiquitin-protein ligase RBX1
UniProt accession	P62877
Gene	RBX1
Organism	Homo sapiens
Length	108 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P62877-F1	alphafold	PREDICTED	79.22	—

Amino-acid sequence (108 residues)

MAAAMDVDTP SGTNSGAGKK RFEVKKWNAV ALWAWDIVVD NCAICRNHIM DLCIECQANQ ASATSEECTV AWGVCNHAFH FHCISRWLKT RQVCPLDNRE WEFQKYGH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards