Large ribosomal subunit protein eL30 (RPL30)

About Large ribosomal subunit protein eL30

Large ribosomal subunit protein eL30 (RPL30) is a protein from Homo sapiens identified by UniProt accession P62888, 115 residues long. MolForge cross-references it against 0 known binders and 52 disease associations.

Target properties

Protein name	Large ribosomal subunit protein eL30
UniProt accession	P62888
Gene	RPL30
Organism	Homo sapiens
Length	115 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (52)

Diseases linked to this target (Open Targets).

Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
influenza · score 0.46
Becker muscular dystrophy · score 0.29
clear cell renal carcinoma · score 0.27
qualitative or quantitative defects of dystrophin · score 0.26
aniridia · score 0.09
diffuse large B-cell lymphoma · score 0.08
hemophilia A · score 0.07
non-Hodgkins lymphoma · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P62888-F1	alphafold	PREDICTED	87.98	—

Amino-acid sequence (115 residues)

MVAAKKTKKS LESINSRLQL VMKSGKYVLG YKQTLKMIRQ GKAKLVILAN NCPALRKSEI EYYAMLAKTG VHHYSGNNIE LGTACGKYYR VCTLAIIDPG DSDIIRSMPE QTGEK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards