Large ribosomal subunit protein eL39 (RPL39)

About Large ribosomal subunit protein eL39

Large ribosomal subunit protein eL39 (RPL39) is a protein from Homo sapiens identified by UniProt accession P62891, 51 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.

Target properties

Protein name	Large ribosomal subunit protein eL39
UniProt accession	P62891
Gene	RPL39
Organism	Homo sapiens
Length	51 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (40)

Diseases linked to this target (Open Targets).

Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
influenza · score 0.46
Becker muscular dystrophy · score 0.29
endometrial cancer · score 0.27
qualitative or quantitative defects of dystrophin · score 0.26
aniridia · score 0.09
diffuse large B-cell lymphoma · score 0.08
epilepsy · score 0.07
non-Hodgkins lymphoma · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P62891-F1	alphafold	PREDICTED	94.00	—

Amino-acid sequence (51 residues)

MSSHKTFRIK RFLAKKQKQN RPIPQWIRMK TGNKIRYNSK RRHWRRTKLG L

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards