Large ribosomal subunit protein eL31 (RPL31)

About Large ribosomal subunit protein eL31

Large ribosomal subunit protein eL31 (RPL31) is a protein from Homo sapiens identified by UniProt accession P62899, 125 residues long. MolForge cross-references it against 0 known binders and 96 disease associations.

Target properties

Protein name	Large ribosomal subunit protein eL31
UniProt accession	P62899
Gene	RPL31
Organism	Homo sapiens
Length	125 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (96)

Diseases linked to this target (Open Targets).

Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
Diamond-Blackfan anemia · score 0.46
influenza · score 0.46
urate measurement · score 0.30
serum alanine aminotransferase measurement · score 0.29
Becker muscular dystrophy · score 0.29
clear cell renal carcinoma · score 0.27
qualitative or quantitative defects of dystrophin · score 0.26
leukocyte count · score 0.25

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P62899-F1	alphafold	PREDICTED	87.95	—

Amino-acid sequence (125 residues)

MAPAKKGGEK KKGRSAINEV VTREYTINIH KRIHGVGFKK RAPRALKEIR KFAMKEMGTP DVRIDTRLNK AVWAKGIRNV PYRIRVRLSR KRNEDEDSPN KLYTLVTYVP VTTFKNLQTV NVDEN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards