About Large ribosomal subunit protein uL1
Large ribosomal subunit protein uL1 (RPL10A) is a protein
from Homo sapiens identified by UniProt accession
P62906, 217 residues long.
MolForge cross-references it against 0 known binders and
86 disease associations.
Target properties
| Protein name | Large ribosomal subunit protein uL1 |
|---|
| UniProt accession | P62906 |
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| Gene | RPL10A |
|---|
| Organism | Homo sapiens |
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| Length | 217 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (86)
Diseases linked to this target (Open Targets).
- Duchenne muscular dystrophy · score 0.50
- cystic fibrosis · score 0.50
- influenza · score 0.46
- Becker muscular dystrophy · score 0.29
- clear cell renal carcinoma · score 0.27
- qualitative or quantitative defects of dystrophin · score 0.26
- thyroid gland adenocarcinoma · score 0.18
- heel bone mineral density · score 0.14
- neurodegenerative disease · score 0.12
- aniridia · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P62906-F1 | alphafold | PREDICTED | 79.20 | — |
Amino-acid sequence (217 residues)
MSSKVSRDTL YEAVREVLHG NQRKRRKFLE TVELQISLKN YDPQKDKRFS GTVRLKSTPR PKFSVCVLGD QQHCDEAKAV DIPHMDIEAL KKLNKNKKLV KKLAKKYDAF LASESLIKQI PRILGPGLNK AGKFPSLLTH NENMVAKVDE VKSTIKFQMK KVLCLAVAVG HVKMTDDELV YNIHLAVNFL VSLLKKNWQN VRALYIKSTM GKPQRLY
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