Large ribosomal subunit protein eL32 (RPL32)

About Large ribosomal subunit protein eL32

Large ribosomal subunit protein eL32 (RPL32) is a protein from Homo sapiens identified by UniProt accession P62910, 135 residues long. MolForge cross-references it against 0 known binders and 104 disease associations.

Target properties

Protein name	Large ribosomal subunit protein eL32
UniProt accession	P62910
Gene	RPL32
Organism	Homo sapiens
Length	135 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (104)

Diseases linked to this target (Open Targets).

Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
influenza · score 0.46
Becker muscular dystrophy · score 0.29
qualitative or quantitative defects of dystrophin · score 0.26
acute myeloid leukemia · score 0.22
lean body mass · score 0.11
body mass index · score 0.11
aniridia · score 0.09
Blackfan-Diamond anemia · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P62910-F1	alphafold	PREDICTED	92.40	—

Amino-acid sequence (135 residues)

MAALRPLVKP KIVKKRTKKF IRHQSDRYVK IKRNWRKPRG IDNRVRRRFK GQILMPNIGY GSNKKTKHML PSGFRKFLVH NVKELEVLLM CNKSYCAEIA HNVSSKNRKA IVERAAQLAI RVTNPNARLR SEENE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards