About Large ribosomal subunit protein uL5
Large ribosomal subunit protein uL5 (RPL11) is a protein
from Homo sapiens identified by UniProt accession
P62913, 178 residues long.
MolForge cross-references it against 0 known binders and
85 disease associations.
Target properties
| Protein name | Large ribosomal subunit protein uL5 |
|---|
| UniProt accession | P62913 |
|---|
| Gene | RPL11 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 178 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (85)
Diseases linked to this target (Open Targets).
- Blackfan-Diamond anemia · score 0.76
- Diamond-Blackfan anemia · score 0.75
- Duchenne muscular dystrophy · score 0.50
- cystic fibrosis · score 0.50
- Short thumb · score 0.46
- influenza · score 0.46
- neurodegenerative disease · score 0.40
- Abnormal radial ray morphology · score 0.37
- Becker muscular dystrophy · score 0.29
- clear cell renal carcinoma · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P62913-F1 | alphafold | PREDICTED | 91.58 | — |
Amino-acid sequence (178 residues)
MAQDQGEKEN PMRELRIRKL CLNICVGESG DRLTRAAKVL EQLTGQTPVF SKARYTVRSF GIRRNEKIAV HCTVRGAKAE EILEKGLKVR EYELRKNNFS DTGNFGFGIQ EHIDLGIKYD PSIGIYGLDF YVVLGRPGFS IADKKRRTGC IGAKHRISKE EAMRWFQQKY DGIILPGK
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