Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A)

About Peptidyl-prolyl cis-trans isomerase FKBP1A

Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) is a protein from Homo sapiens identified by UniProt accession P62942, 108 residues long. MolForge cross-references it against 0 known binders and 637 disease associations.

Target properties

Protein name	Peptidyl-prolyl cis-trans isomerase FKBP1A
UniProt accession	P62942
Gene	FKBP1A
Organism	Homo sapiens
Length	108 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (8)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (637)

Diseases linked to this target (Open Targets).

atopic eczema · score 0.60
acute graft vs. host disease · score 0.59
renal cell carcinoma · score 0.59
chronic kidney disease · score 0.59
dermatitis, atopic · score 0.59
coronary artery disease · score 0.58
breast cancer · score 0.58
kidney disease · score 0.58
kidney failure · score 0.58
cytomegalovirus infection · score 0.58

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P62942-F1	alphafold	PREDICTED	96.27	—

Amino-acid sequence (108 residues)

MGVQVETISP GDGRTFPKRG QTCVVHYTGM LEDGKKFDSS RDRNKPFKFM LGKQEVIRGW EEGVAQMSVG QRAKLTISPD YAYGATGHPG IIPPHATLVF DVELLKLE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards