Apoptosis inducing factor BLCAP (BLCAP)

About Apoptosis inducing factor BLCAP

Apoptosis inducing factor BLCAP (BLCAP) is a protein from Homo sapiens identified by UniProt accession P62952, 87 residues long. MolForge cross-references it against 0 known binders and 88 disease associations.

Target properties

Protein name	Apoptosis inducing factor BLCAP
UniProt accession	P62952
Gene	BLCAP
Organism	Homo sapiens
Length	87 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (88)

Diseases linked to this target (Open Targets).

body height · score 0.22
neoplasm · score 0.08
vital capacity · score 0.08
Romano-Ward syndrome · score 0.06
rheumatoid arthritis · score 0.06
Familial short QT syndrome · score 0.06
Arrhythmogenic right ventricular dysplasia · score 0.06
Brugada syndrome · score 0.06
MODY · score 0.05
familial atrial fibrillation · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P62952-F1	alphafold	PREDICTED	62.73	—

Amino-acid sequence (87 residues)

MYCLQWLLPV LLIPKPLNPA LWFSHSMFMG FYLLSFLLER KPCTICALVF LAALFLICYS CWGNCFLYHC SDSPLPESAH DPGVVGT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards