About Voltage-dependent calcium channel gamma-7 subunit
Voltage-dependent calcium channel gamma-7 subunit (CACNG7) is a protein
from Homo sapiens identified by UniProt accession
P62955, 275 residues long.
MolForge cross-references it against 0 known binders and
31 disease associations.
Target properties
| Protein name | Voltage-dependent calcium channel gamma-7 subunit |
|---|
| UniProt accession | P62955 |
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| Gene | CACNG7 |
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| Organism | Homo sapiens |
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| Length | 275 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (31)
Diseases linked to this target (Open Targets).
- cardiovascular disease · score 0.46
- generalized anxiety disorder · score 0.39
- Urinary incontinence · score 0.37
- Polyuria · score 0.37
- gastrointestinal disease · score 0.37
- mathematical ability · score 0.34
- benign eyelid neoplasm · score 0.32
- neurodegenerative disease · score 0.30
- anxiety · score 0.27
- Intellectual disability · score 0.26
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P62955-F1 | alphafold | PREDICTED | 71.88 | — |
Amino-acid sequence (275 residues)
MSHCSSRALT LLSSVFGACG LLLVGIAVST DYWLYMEEGT VLPQNQTTEV KMALHAGLWR VCFFAGREKG RCVASEYFLE PEINLVTENT ENILKTVRTA TPFPMVSLFL VFTAFVISNI GHIRPQRTIL AFVSGIFFIL SGLSLVVGLV LYISSINDEV MNRPSSSEQY FHYRYGWSFA FAASSFLLKE GAGVMSVYLF TKRYAEEEMY RPHPAFYRPR LSDCSDYSGQ FLQPEAWRRG RSPSDISSDV SIQMTQNYPP AIKYPDHLHI STSPC
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