Ubiquitin-ribosomal protein eS31 fusion protein…

About Ubiquitin-ribosomal protein eS31 fusion protein

Ubiquitin-ribosomal protein eS31 fusion protein (RPS27A) is a protein from Homo sapiens identified by UniProt accession P62979, 156 residues long. MolForge cross-references it against 0 known binders and 94 disease associations.

Target properties

Protein name	Ubiquitin-ribosomal protein eS31 fusion protein
UniProt accession	P62979
Gene	RPS27A
Organism	Homo sapiens
Length	156 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (94)

Diseases linked to this target (Open Targets).

cystic fibrosis · score 0.61
HIV infection · score 0.57
listeriosis · score 0.53
cancer · score 0.51
Duchenne muscular dystrophy · score 0.50
severe acute respiratory syndrome · score 0.50
COVID-19 · score 0.46
Diamond-Blackfan anemia · score 0.46
tuberculosis · score 0.46
influenza · score 0.46

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P62979-F1	alphafold	PREDICTED	89.56	—

Amino-acid sequence (156 residues)

MQIFVKTLTG KTITLEVEPS DTIENVKAKI QDKEGIPPDQ QRLIFAGKQL EDGRTLSDYN IQKESTLHLV LRLRGGAKKR KKKSYTTPKK NKHKRKKVKL AVLKYYKVDE NGKISRLRRE CPSDECGAGV FMASHFDRHY CGKCCLTYCF NKPEDK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Ubiquitin-ribosomal protein eS31 fusion protein (RPS27A)