Ras-related C3 botulinum toxin substrate 1 (RAC1)

About Ras-related C3 botulinum toxin substrate 1

Ras-related C3 botulinum toxin substrate 1 (RAC1) is a protein from Homo sapiens identified by UniProt accession P63000, 192 residues long. MolForge cross-references it against 0 known binders and 271 disease associations.

Target properties

Protein name	Ras-related C3 botulinum toxin substrate 1
UniProt accession	P63000
Gene	RAC1
Organism	Homo sapiens
Length	192 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (1)

DrugCentral-linked approved drugs that act on this protein.

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P63000-F1	alphafold	PREDICTED	93.84	—

Amino-acid sequence (192 residues)

MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDGKP VNLGLWDTAG QEDYDRLRPL SYPQTDVFLI CFSLVSPASF ENVRAKWYPE VRHHCPNTPI ILVGTKLDLR DDKDTIEKLK EKKLTPITYP QGLAMAKEIG AVKYLECSAL TQRGLKTVFD EAIRAVLCPP PVKKRKRKCL LL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards