Dynein light chain 1, cytoplasmic (DYNLL1)

About Dynein light chain 1, cytoplasmic

Dynein light chain 1, cytoplasmic (DYNLL1) is a protein from Homo sapiens identified by UniProt accession P63167, 89 residues long. MolForge cross-references it against 0 known binders and 139 disease associations.

Target properties

Protein name	Dynein light chain 1, cytoplasmic
UniProt accession	P63167
Gene	DYNLL1
Organism	Homo sapiens
Length	89 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (139)

Diseases linked to this target (Open Targets).

viral disease · score 0.46
coenzyme q10 deficiency, primary, 9 · score 0.33
low grade glioma · score 0.28
mean corpuscular volume · score 0.26
neurodegenerative disease · score 0.25
head and neck squamous cell carcinoma · score 0.23
endometrial cancer · score 0.23
urinary bladder cancer · score 0.23
mean reticulocyte volume · score 0.21
reticulocyte count · score 0.21

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P63167-F1	alphafold	PREDICTED	95.34	—

Amino-acid sequence (89 residues)

MCDRKAVIKN ADMSEEMQQD SVECATQALE KYNIEKDIAA HIKKEFDKKY NPTWHCIVGR NFGSYVTHET KHFIYFYLGQ VAILLFKSG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards