Dynein light chain Tctex-type 1 (DYNLT1)

About Dynein light chain Tctex-type 1

Dynein light chain Tctex-type 1 (DYNLT1) is a protein from Homo sapiens identified by UniProt accession P63172, 113 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.

Target properties

Protein name	Dynein light chain Tctex-type 1
UniProt accession	P63172
Gene	DYNLT1
Organism	Homo sapiens
Length	113 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (49)

Diseases linked to this target (Open Targets).

alkaline phosphatase measurement · score 0.16
protein measurement · score 0.09
glioblastoma multiforme · score 0.08
breast cancer · score 0.07
neoplasm · score 0.05
lipoprotein A measurement · score 0.04
triple-negative breast cancer · score 0.02
cancer · score 0.02
Huntington disease · score 0.02
glioblastoma · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P63172-F1	alphafold	PREDICTED	95.11	—

Amino-acid sequence (113 residues)

MEDYQAAEET AFVVDEVSNI VKEAIESAIG GNAYQHSKVN QWTTNVVEQT LSQLTKLGKP FKYIVTCVIM QKNGAGLHTA SSCFWDSSTD GSCTVRWENK TMYCIVSAFG LSI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards