Large ribosomal subunit protein eL38 (RPL38)

About Large ribosomal subunit protein eL38

Large ribosomal subunit protein eL38 (RPL38) is a protein from Homo sapiens identified by UniProt accession P63173, 70 residues long. MolForge cross-references it against 0 known binders and 478 disease associations.

Target properties

Protein name	Large ribosomal subunit protein eL38
UniProt accession	P63173
Gene	RPL38
Organism	Homo sapiens
Length	70 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (478)

Diseases linked to this target (Open Targets).

Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
influenza · score 0.46
Becker muscular dystrophy · score 0.29
qualitative or quantitative defects of dystrophin · score 0.26
protein measurement · score 0.20
artificial cardiac pacemaker · score 0.18
PHF-tau measurement · score 0.13
DNA methylation · score 0.13
aniridia · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P63173-F1	alphafold	PREDICTED	95.35	—

Amino-acid sequence (70 residues)

MPRKIEEIKD FLLTARRKDA KSVKIKKNKD NVKFKVRCSR YLYTLVITDK EKAEKLKQSL PPGLAVKELK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards