Guanine nucleotide-binding protein G(T) subunit…

About Guanine nucleotide-binding protein G(T) subunit gamma-T1

Guanine nucleotide-binding protein G(T) subunit gamma-T1 (GNGT1) is a protein from Homo sapiens identified by UniProt accession P63211, 74 residues long. MolForge cross-references it against 0 known binders and 94 disease associations.

Target properties

Protein name	Guanine nucleotide-binding protein G(T) subunit gamma-T1
UniProt accession	P63211
Gene	GNGT1
Organism	Homo sapiens
Length	74 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (94)

Diseases linked to this target (Open Targets).

body mass index · score 0.37
lean body mass · score 0.35
hematocrit · score 0.30
sex hormone-binding globulin measurement · score 0.29
thyroid gland adenocarcinoma · score 0.28
appendicular lean mass · score 0.27
hip circumference · score 0.26
gastric adenocarcinoma · score 0.24
lung adenocarcinoma · score 0.24
hepatocellular carcinoma · score 0.22

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P63211-F1	alphafold	PREDICTED	88.41	—

Amino-acid sequence (74 residues)

MPVINIEDLT EKDKLKMEVD QLKKEVTLER MLVSKCCEEV RDYVEERSGE DPLVKGIPED KNPFKELKGG CVIS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Guanine nucleotide-binding protein G(T) subunit gamma-T1 (GNGT1)