About Eukaryotic translation initiation factor 5A-1
Eukaryotic translation initiation factor 5A-1 (EIF5A) is a protein
from Homo sapiens identified by UniProt accession
P63241, 154 residues long.
MolForge cross-references it against 0 known binders and
86 disease associations.
Target properties
| Protein name | Eukaryotic translation initiation factor 5A-1 |
|---|
| UniProt accession | P63241 |
|---|
| Gene | EIF5A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 154 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (86)
Diseases linked to this target (Open Targets).
- Faundes-Banka syndrome · score 0.67
- neurodegenerative disease · score 0.46
- complex neurodevelopmental disorder · score 0.37
- sex hormone-binding globulin measurement · score 0.27
- Neurodevelopmental disorder · score 0.27
- blood phosphate measurement · score 0.21
- body height · score 0.21
- mathematical ability · score 0.18
- bilirubin measurement · score 0.16
- venous thromboembolism · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P63241-F1 | alphafold | PREDICTED | 88.64 | — |
Amino-acid sequence (154 residues)
MADDLDFETG DAGASATFPM QCSALRKNGF VVLKGRPCKI VEMSTSKTGK HGHAKVHLVG IDIFTGKKYE DICPSTHNMD VPNIKRNDFQ LIGIQDGYLS LLQDSGEVRE DLRLPEGDLG KEIEQKYDCG EEILITVLSA MTEEAAVAIK AMAK
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