About Y-box-binding protein 1
Y-box-binding protein 1 (YBX1) is a protein
from Homo sapiens identified by UniProt accession
P67809, 324 residues long.
MolForge cross-references it against 0 known binders and
286 disease associations.
Target properties
| Protein name | Y-box-binding protein 1 |
|---|
| UniProt accession | P67809 |
|---|
| Gene | YBX1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 324 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (286)
Diseases linked to this target (Open Targets).
- neoplasm · score 0.12
- cancer · score 0.11
- breast cancer · score 0.11
- hepatocellular carcinoma · score 0.11
- triple-negative breast cancer · score 0.11
- renal cell carcinoma · score 0.11
- non-small cell lung carcinoma · score 0.10
- melanoma · score 0.10
- acute myeloid leukemia · score 0.10
- urinary bladder carcinoma · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P67809-F1 | alphafold | PREDICTED | 61.83 | — |
Amino-acid sequence (324 residues)
MSSEAETQQP PAAPPAAPAL SAADTKPGTT GSGAGSGGPG GLTSAAPAGG DKKVIATKVL GTVKWFNVRN GYGFINRNDT KEDVFVHQTA IKKNNPRKYL RSVGDGETVE FDVVEGEKGA EAANVTGPGG VPVQGSKYAA DRNHYRRYPR RRGPPRNYQQ NYQNSESGEK NEGSESAPEG QAQQRRPYRR RRFPPYYMRR PYGRRPQYSN PPVQGEVMEG ADNQGAGEQG RPVRQNMYRG YRPRFRRGPP RQRQPREDGN EEDKENQGDE TQGQQPPQRR YRRNFNYRRR RPENPKPQDG KETKAADPPA ENSSAPEAEQ GGAE
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