About Casein kinase II subunit beta
Casein kinase II subunit beta (CSNK2B) is a protein
from Homo sapiens identified by UniProt accession
P67870, 215 residues long.
MolForge cross-references it against 0 known binders and
140 disease associations.
Target properties
| Protein name | Casein kinase II subunit beta |
|---|
| UniProt accession | P67870 |
|---|
| Gene | CSNK2B |
|---|
| Organism | Homo sapiens |
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| Length | 215 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (140)
Diseases linked to this target (Open Targets).
- Poirier-Bienvenu neurodevelopmental syndrome · score 0.76
- neurodegenerative disease · score 0.54
- genetic disorder · score 0.52
- autosomal dominant non-syndromic intellectual disability · score 0.44
- Neurodevelopmental disorder · score 0.43
- neuroinflammatory disorder · score 0.37
- Parkinson disease · score 0.34
- Intellectual disability · score 0.34
- Alzheimer disease · score 0.33
- lysosomal storage disease · score 0.33
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P67870-F1 | alphafold | PREDICTED | 93.57 | — |
Amino-acid sequence (215 residues)
MSSSEEVSWI SWFCGLRGNE FFCEVDEDYI QDKFNLTGLN EQVPHYRQAL DMILDLEPDE ELEDNPNQSD LIEQAAEMLY GLIHARYILT NRGIAQMLEK YQQGDFGYCP RVYCENQPML PIGLSDIPGE AMVKLYCPKC MDVYTPKSSR HHHTDGAYFG TGFPHMLFMV HPEYRPKRPA NQFVPRLYGF KIHPMAYQLQ LQAASNFKSP VKTIR
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